The mosaic theory 32 years later.

The mosaic theory 32 years later.

T has been 32 years since the mosaic theory was proposed. In principle it has not been widely accepted , although in practice generally employed. The principle seems not to have been clearly understood , albeit the concept that hypertension is a multi-factoral, multifaceted disease is current. Understanding the principle depends upon appreciating chemical equilibria, especially as exemplified b...

The danger theory: 20 years later

The self-non-self theory has dominated immunology since the 1950s. In the 1990s, Matzinger and her colleagues suggested a new, competing theory, called the "danger theory." This theory has provoked mixed acclaim: enthusiasm and criticism. Here we assess the danger theory vis-à-vis recent experimental data on innate immunity, transplantation, cancers and tolerance to foreign entities, and try to...

Keynes’s General Theory Seventy-Five Years Later

This year will be the eightieth anniversary of the publication of the General Theory. It will also be seventy years since the death of John Maynard Keynes and I am sure that new volumes will appear to add new interpretations or develop ideas derived from the book that radically changed economics and policy making. This year will also mark twenty years since the death of Hyman Minsky, who analyz...

Indoor radon entry: 30 years later

The paper discusses the results of 30 years of radon indoor entry research. While some progress has been made, many discrepancies between current theories and experimental data still remain. Misconceptions of radon transport mechanisms in homes are analyzed. The role of US Environmental Protection Agency in radon indoor entry research is examined and the agency's policies are criticize...

Game Theory and Operations Research: Some Musings 50 Years Later